GB-COH-04465125-NIHR-P83165 Imperial College of Science, Technology and Medicine The aim of our program is to examine if a pragmatic, evidenced based and generalisable intrapartum care bundle (includes 4 elements birth companion, intelligent auscultation, electronic medical care record, brain oriented neonatal resuscitation) will reduce birth injury related epilepsy at 18 months of age in three public sector hospitals in India. Imperial is the lead institution. University College London is lead for neonatal aEEG and seizure diagnosis. University of Manchester and Liverpool School for Tropical Medicine are lead for birth companion element of care bundle, University of Oxford is lead for Epilepsy and Veevan Ventures is the coordinating site for the participating sites in India. Objectives:(1) To examine if a pragmatic, evidenced based and generalisable intrapartum care bundle involving birth companions and empowering mothers will reduce birth injury related epilepsy at 18 months of age in India.(2) If effective, incorporate care bundle into the Labour Room Quality Improvement (LaQshya) programme, for national implementation, thus averting approximately 50,000 epilepsy cases every year in India.(3) Provide opportunities for academic and clinical capacity building in India in midwifery, neonatal/paediatric neurology and epilepsy, and public health. National Institute of Health Research (NIHR) Imperial College of Science, Technology and Medicine The University of Manchester Liverpool School of Tropical Medicine The University of Oxford Veevan Ventures University College London Perinatal Brain Research Centre Indian Institute of Health Management Research 2192895.56 3340239 2184608.82 136375 27710 23367.39 1537824 194901 52712 105891 GB-COH-04465125-NIHR-P89503 Imperial College of Science, Technology and Medicine Physical trauma resulting in serious, life changing injuries is endemic in Low- and Middle-Income Countries (LMICs). This project builds on prior work through an understanding of the broader global burden of physical trauma from conflict, non-conflict events such as terror attacks and the growing burden of road traffic accidents due to rapid increases in urbanisation and motor vehicle use. This project works across three continents and will collaborate with some of the largest humanitarian organisations to make change happen. Imperial College London, UK is Co-director of the project and will work on most of the aims. University of Global Health Equity, Rwanda, is the other Co-director and will head the translation activities there with the help of the University of Rwanda. The American University of Beirut, Lebanon, leads on the burden of injury work in the 2006 Lebanon war and gunshot wound project in Gaza. Finally, University of Moratuwa, Sri Lanka, are working on regenerative medicine aspects within the project. National Institute of Health Research (NIHR) Imperial College of Science, Technology and Medicine University of Global Health Equity University of Rwanda American University of Beirut University of Moratuwa Legacy of War Foundation 1256816 107141 1333545.73 203446.06 99397.73 453995.46 41963.67 2047 GB-COH-04465125-NIHR-P89685 Imperial College of Science, Technology and Medicine Our Global Health Research Network is a partnership between research intensive organisations BRAC in Bangladesh, MDRF and DDF in India, SIMS in Pakistan, UKEL and UCOL in Sri Lanka and the UK, and key collaborators in Australia and Singapore.Our primary ambitions are to: i. improve understanding of the mechanisms underlying the high burdenof Type-2 diabetes (T2D) and cardiovascular disease (CVD) in South Asians, and ii. improve prevention and control of these major diseases through personalised, health systems and policy-based interventions, that are scalable, sustainable, effective and equitable. National Institute of Health Research (NIHR) University of Colombo Nanyang Technological University University of Kelaniya Devki Devi Foundation Services Institute of Medical Sciences BRAC University Madras Diabetes Research Foundation Imperial College of Science, Technology and Medicine 3930992 414471.5 2460343.02 712660 4797188.57 390351.43 172089.1 361121.02 17399 392250.97 GB-COH-04465125-NIHR-P90834 Imperial College of Science, Technology and Medicine Liverpool School of Tropical Medicine is the lead institute for the study. Imperial College is involved in WS6, which involves evaluating how best to support parents, families, attending health providers and communities who experience a stillbirth or neonatal death in India and WS5 which focuses on improving immediate new-born care and resuscitation and parent's involvement in care of sick babies in India. National Institute of Health Research (NIHR) Liverpool School of Tropical Medicine International Perinatal Epidemiology Unit Private Limited Imperial College of Science, Technology and Medicine 467671 467671.42 44510 44509.8 GB-COH-04465125-DESNZ-P91322 Imperial College of Science, Technology and Medicine Agroforestry systems for Organic Cotton production (OAC) seek to play a pivotal role in addressing climate change and supporting a green and inclusive recovery in Brazil. AGROcotton seeks to build capacity for OAC production and develop scalable business models for sustainable OAC supply chains in Brazil, contributing to; (i) sustained reduction of GHG emissions, (ii) greenand resilient recovery reducing deforestation, biodiversity loss and water stress, and (iii) inclusive recovery generating income opportunities for marginalised communities. AGROcotton sorted deliver:1. Spatial analysis of land suitability and potentials of OAC in Brazil (ICL). To promote the outcome, Task 1 will facilitate the scale-up and replicability of OAC projects employ GIS-based Multi-Criteria Analysis to quantify suitable areas (high, medium and low suitability) and geolocate most suitable areas in the Midwest, Northeast and North regions of Brazil.2. Capacity building in Mato Grosso (FF & ICL). To advance the outcome, Task 2 will improve the capacity of small-scale farmers to implement OAC systems by training between 20 and 100 small-scale, vulnerable farmers on financial, management and agricultural aspects of OAC systems.3. Implementation of OAC pilot cases in Mato Grosso (FF & ICL). To promote the outcome, Task 3 will generate experience with the execution of OAC systems by cultivating 20 ha of degraded forest integrating cotton with other crops.4. Environmental analyses (ICL & FF). To advance the outcome, Task 4 will provide critical knowledge of the environmental impacts of OAC systems by quantifying emissions of Greenhouse Gases, consumption and pollution of water and impacts on biodiversity with Life Cycle approach, based on experimental data from Mato Grosso. Also, changes of land use and land cover, both direct and indirect, will be monitored and quantified. 5. Socio-economic and financial analyses (ICL & FF). To promote the outcome, Task 5 will analyse the financial and socio-economic impacts of OAC systems at farm level, based on experimental data from Mato Grosso. 6. AGROcotton guidelines for OAC (FF & ICL). To advance the outcome, Task 6 will facilitate the replicability of OAC projects and inspire future action by developing a set of OAC guidelines synthetizing empirical evidence and lessons learnt from T2, 3, 4 and 5 of AGROcotton. 7. Market analysis (UB & FF). To promote the outcome, Task 7 will characterise the potential market of OAC in Brazil by mapping supply chain actors and drivers, considering prices, willingness to pay and the importance of traceability and certification. 8. Policy analysis and recommendations (UB). To promote the outcome, Task 5 will recommend policies and programmes for OAC systems in Brazil (UB). To promote the outcome, Task 5 will recommend policies and programmes for OAC systems in Brazil based on an analysis of existing policies in agriculture and forestry and expert interviews. 9. Dissemination and communication activities (FF, ICL & UB). To advance the outcome, Task 6 will communicate and disseminate widely the outputs of AGROcotton and by initiating the establishment of a national stakeholder platform for OAC. Imperial College of Science, Technology and Medicine FarFarm University of Brasília Department for Energy Security and Net Zero (DESNZ) Identifier changed to GB-COH-04465125-DESNZ_P91332 to reflect funding organisation 305306.40 140729.26 174409.51 Imperial College London Farfarm Consultoria Ltda 129247.70 176058.98 GB-COH-04465125-NIHR-P88207 Imperial College of Science, Technology and Medicine Efforts by low and middle income countries (LMICs) to achieve universal health coverage (UHC) are often constrained by inadequate resources. As demands on health systems expand, pressure to contain costs can threaten quality, including the quality of medicines on which all health systems rely. While the WHO believes substandard and falsified medicines (S&F meds) are on the rise, there are no agreed methods for measuring the problem, and thus no way of tracking progress in ensuring that medicines newly available to poorer patients through UHC efforts are safe and effective. Indonesia has vastly expanded its national health insurance since 2014; it now undertakes to provide free medicine to 222 million people, over 80% of citizens in the world's fourth most populous nation. Procurement policies that prioritise low cost over quality aim to reduce the deficit of £1.9 bln but have raised concerns, magnified by several recent scandals, that UHC is expanding access to S&F meds. Objectives: We aim to support national efforts to ensure that Indonesians, especially the poorest who rely on insurance or informal markets, have consistent access to quality medicine. We will do this by working with the medicine regulator and intersectoral partners to better understand and quantify the prevalence and distribution of S&F meds nationally. In the process, we will:1. Trial new methods for risk-based sentinel surveillance for S&F meds;2. Develop robust, adaptable tools to estimate the prevalence, health impact and cost of S&F meds;3. Pioneer the use of the tools, making the first national estimates of S&F meds in any LMIC;4. Engage continuously with policy partners to facilitate appropriate intersectoral responses in Indonesia, and to adapt tools for other LMICs.5) Promote institutionalisation of academic-policy partnerships to support the ongoing production and use of medicine policy research in Indonesia. National Institute of Health Research (NIHR) Universitas Pancasila Erasmus University Imperial College of Science, Technology and Medicine Health statistics and data Collection, production, management and dissemination of statistics and data related to health. Includes health surveys, establishment of health databases, data collection on epidemics, etc. 2041486.64 2043030.64 2040944.18 145919.64 GB-COH-04465125-NIHR-P94067 Imperial College of Science, Technology and Medicine The way health systems are structured and financed has major implications for the quality and comprehensiveness of the services they deliver, whether patients use those services, how much they cost and who pays, and whether they deliver improvements in health outcomes. In many low- and middle-income countries (LMICs) health financing is highly fragmented and can negatively impact health system goals including ensuring access to high quality care to all patients, irrespective of their ability to pay. This research programme generates evidence from four countries: Brazil, Colombia, Mexico and India. The research aims to quantify the nature and variation of financing fragmentation in the four countries, investigate how financing fragmentation affects health system goals, and understand the political factors which drive financing fragmentation. https://hs-fragmentation.org/ Imperial College of Science, Technology and Medicine University of York O.P. Jindal Global University Universidad Nacional de Colombia National Institute of Public Health of Mexico (INSP) Instituto De Estudos Para Políticas Da Saúde (IEPS) National Institute of Health Research (NIHR) 3109465 284721 467880 2166289.31 570861 375556 451274 2150292.31 GB-COH-04465125-NIHR-PA1845 Imperial College of Science, Technology and Medicine The NIHR Global Health Research Centre for non-communicable diseases (NCDs) and Environmental Change will be a recognised centre of excellence on NCDs and global environmental change in low and middle-income countries (LMICs), offering world-leading research, training and policy advice for health equity within 5 years. It includes four LMIC-based institutions working in three countries, Bangladesh, India, and Indonesia. The target NCDs are hypertension, diabetes, cardiovascular diseases (CVD), chronic kidney disease (CKD) and Chronic obstructive pulmonary disease (COPD).The Centre addresses crucial knowledge gaps through three integrated research themes: •Strengthening primary health care and essential public health services for NCD prevention and management in communities affected by rapid environmental change; •Developing and evaluating multi-sectoral interventions that have dual benefits in reducing the burden of NCDs and hazardous environmental exposures at the population level; •Strengthening engagement of communities in the generation and use of evidence and advocacy for health and environment policy change.The Centre focusses on strengthening primary health care through establishment of a digital platform, and developing and evaluating multi-sectoral interventions addressing coastal water salinity and hypertension in Bangladesh, leveraging food aid for NCD prevention in India and reducing effects of plastics burning and air pollution in Indonesia. Community engagement and involvement activities will be key in the evidence-to-policy process in each of the research focus areas to identify opportunities for strengthening impact outcomes.Throughout the research lifecycle, the Centre emphasises systematic and meaningful engagement of community members and policymakers – including through co-design and evaluation of interventions. In addition to delivering high-quality impactful research, research capacity strengthening is a top priority. The Centre is delivering several training and development opportunities targeting three critical career periods: (1) pre-doctoral, (2) early post-doctoral and (3) transitioning to senior leadership.The Centre’s Theory of Change aims to bring positive impact through:-•Enhanced health equity, wellbeing and environmental sustainability across Asia (SDGs 3, 5, 10, 13, and 17); •Strengthened research infrastructure for generating high-quality evidence on NCDs in populations most vulnerable to environmental change; •Mobilised CEI capability to ensure evidence, advocacy and policy action is community-centric and benefits the most vulnerable. Brawijaya University Sri Ramachandra Institute of Higher Education and Research University of Portsmouth Imperial College of Science, Technology and Medicine George Institute for Global Health International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b) UK - Department of Health and Social Care (DHSC) The Manchester Metropolitan University 7311216 3748752.16 3807443 972125.91 930955.82 1372338 457260 14241.3 1831.13 GB-COH-04465125-BMPF-P67348 Imperial College of Science, Technology and Medicine The NIHR Global Health Research Group on Post Conflict Trauma; PrOTeCT, was a collaborative grant between Imperial College London (UK), the University of Moratuwa (Sri Lanka) and the American University of Beirut (Lebanon). It brought together expertise in trauma practice, engineering and clinical research. The clinical goal for this NIHR Group was limb salvage for victims of conflict trauma. Within the lifetime of the grant, and beyond, we aimed to deliver measurable benefits to people in LMIC countries who have suffered injuries as a result of conflicts. We wanted to identify the types of injuries that have led to early amputation and those which are amendable to salvage. In addition, we aimed to develop and to clinically deploy technology for limb salvage and limb regeneration that will be appropriate wherever blast injuries occur. To achieve this, we had the following research aims: 1) Identify patient characteristics that have led to early avoidable amputation; 2) Provide immediate surgeon education for limb salvage/amputation using state of the art techniques; 3) Develop simple, low cost bespoke instruments and implantable devices to maximise the extent of limb salvage. The PrOTeCT Group successful designed an external fixator for use after traumatic injury, progressed regenerative medicine scaffolds towards future use in limb salvage and gained insights into the clinical burden of war injuries. Imperial College of Science, Technology and Medicine American University of Beirut University of Moratuwa National Institute of Health Research (NIHR) 2365936.46 2179335.05 2247640.79 GB-COH-04465125-NIHR-P68219 Imperial College of Science, Technology and Medicine The Programme is now complete. Our Global Health Research Unit has focussed on research for the benefit of people living in Bangladesh, India, Pakistan and Sri Lanka. In collaboration with our research partners in South Asia: BRAC in Bangladesh, MDRF and DDF in India, SIMS in Pakistan, UKEL and UCOL in Sri Lanka and the UK, and key collaborators in Australia and Singapore. National Institute of Health Research (NIHR) Imperial College of Science, Technology and Medicine Nanyang Technological University University of Kelaniya Devki Devi Foundation University of Colombo 6997610 6804737.32 6768449.43 GB-COH-04465125-NIHR-P82837 Imperial College of Science, Technology and Medicine Development grant to build collaborations, stakeholder engagement, and priority setting for larger research grant on health systems research. Partners include Instituto De Estudos Para Políticas Da Saúde (IEPS) in Brazil and National Institute of Public Health in Mexico. Instituto De Estudos Para Políticas Da Saúde (IEPS) National Institute of Public Health National Institute of Health Research (NIHR) Imperial College of Science, Technology and Medicine 92245.22 98087.91 96845.22 GB-COH-04465125-NIHR-PA3631 Imperial College of Science, Technology and Medicine Health systems in LMICs are poorly equipped to care for chronic mental and physical disease, which are rapidly increasing with aging populations. Cognitive impairment challenges health systems on multiple fronts, incurring huge human and financial costs. Latin America has the highest projected increase in dementia incidence globally, and in Peru there are ~300,000 people with dementia (PWD). Many are undiagnosed and lack basic support. Care is often provided exclusively by family members. IMPACT Dement is a new 4-year project funded by the Global Health programme of the NIHR, which will tackle inequity in access to dementia care and diagnosis in Peru and beyond using sustainable, integrated, person-centred, community-delivered, technology-enabled innovation. https://impact-salud.org Imperial College of Science, Technology and Medicine University of Cardiff Universidad Peruana Cayetano Heredia University of Edinburgh The University of Oxford University of Sydney 3139619 987239 1647768 46477 102175 23283 1212771 GB-COH-04465125-NIHRPB0552 Imperial College of Science, Technology and Medicine "Project Summary The NIHR STOP-HBV project is a multi-country global health research programme funded by the National Institute for Health and Care Research (NIHR) and led by Imperial College London. The project aims to strengthen hepatitis B virus (HBV) prevention, diagnosis, and care pathways in sub-Saharan Africa, contributing to progress towards WHO hepatitis elimination targets. HBV remains a major cause of liver cirrhosis and liver cancer in Africa, with limited access to systematic screening, laboratory monitoring, and long-term antiviral treatment. STOP-HBV addresses these gaps through implementation research embedded within routine health systems. The project combines clinical research, laboratory strengthening, capacity building, and policy translation to develop scalable and sustainable models of care. The programme focuses on improving: • Identification of pregnant women and adults living with chronic HBV • Linkage to specialist liver care • Access to antiviral treatment • Monitoring of liver disease progression • Integration of HBV services within national health systems The project also strengthens local research capacity through training of PhD students, project managers, and clinical researchers, and supports institutional governance and data management systems. Countries Involved and Specific Roles: United Kingdom Imperial College London (Lead Contractor and Sponsor) Imperial College London leads and coordinates the overall project. Responsibilities include: • Scientific leadership (Chief Investigator: Prof. Maud Lemoine) • Overall project governance and management • Sponsor responsibilities and regulatory oversight • Central financial management • Contracts and partner agreements The Gambia MRC Unit The Gambia at the London School of Hygiene & Tropical Medicine (LSHTM) The Gambia site hosts the West African implementation component of STOP-HBV. Responsibilities include: • Participant recruitment and follow-up within antenatal and clinical services • Delivery of HBV screening and clinical management • Laboratory testing (virology and liver disease assessment) • Local data collection and management • Engagement with the Ministry of Health for translation into policy • Contribution to scientific outputs and dissemination University of Liverpool (UK) The University of Liverpool collaborates through its long-standing partnership with MLW. Responsibilities include: • Academic oversight and co-investigator input • Clinical research leadership in Malawi (Dr Alexander Stockdale and collaborators) • Data analysis and interpretation • Contribution to publications and capacity building United Kingdom Canterbury Christ Church University (CCCU) • Implementation science and public health expertise • Support for evaluation methodology and health systems analysis • Contribution to capacity building and training activities • Participation in dissemination and knowledge translation CCCU contributes academic expertise but does not hold ownership of in-country Research Data. Malawi Kamuzu University of Health Sciences (KUHeS) • National academic partner in Malawi • Integration of research within medical education and health workforce development • Clinical collaboration through QECH • Strengthening institutional research capacity • Contribution to sustainability and translation into national policy Coolaborators do also include: Malawi Liverpool Wellcome Programme (MLW) Governmental health facilities The Gambia Young Gambian Fund, The Gambia World Hepatitis Alliance • Host institution for Malawi implementation site • Embedded within Queen Elizabeth Central Hospital (QECH), Blantyre • Recruitment and follow-up of pregnant women • Laboratory diagnostics and viral load monitoring • Implementation research and community engagement • Local regulatory compliance and governance " MRC Unit The Gambia at the London School of Hygiene & Tropical Medicine (MRCG) Kamuzu University of Health Sciences (KUHeS) University of Liverpool Canterbury Christ Church University 71% of the funds are allocated to LMICs partner. 71% of the funds are allocated to LMICs partner. 2966810.77 880050 64250 402152 1223336 GB-COH-04465125-NIHR-P93366 Imperial College of Science, Technology and Medicine The Project aims to investigate whether a new type of diagnostic test, called a digital diagnostic, will be better than currently available diagnostic tests in African health care settings. We aim to evaluate whether digital diagnostics technology will work properly, whether it will provide accurate diagnoses, and whether we can optimise it to give the maximum chance that it is adopted intopractice in African healthcare systems. To do this, we need to fully understand the context in which it will be used, and understand the perspectives of all of those who might be impacted, from the patients and healthcare workers right up to ministries of health and international policy makers. We do this through different types of interviews and focus groups. We optimise the design of digital diagnostics in partnership with the intended users – so called “co-design”. We assess the potential impact on health systems to understand how other aspects of diagnosis and care might be affected. We compare accuracy of diagnoses using our digital diagnostics technology against those of the best possible "gold standard" diagnostic tests, and also against any tests in common use in Africa.We want to look at different scenarios where there are important gaps in the availability, accuracy, or data collection from currentdiagnostic tests. These scenarios are: 1. detection of malaria parasites; 2. cause of fever in young children; 3. detecting bacterial contamination of water and food. The countries where the research is underatken are: - The Gambia - Ghana - Burkina Faso - Kenya - Sudan - Zambia The research plan is structured in 6 cross-cutting Work Packages and 10 Sub-Projects as follows: WP1 | Technology Development Lead: Prof. Pantelis Georgiou (Imperial College London)WP2 | Community Engagement and InvolvementLead: Prof. Salome Bukachi (University of Nairobi)WP3 | Diagnostic Evaluation Leads: Dr Jane Achan (Malaria Consortium), Dr Samuel Duodu (University of Ghana)WP4 | Health Systems Lead: Dr Julie Balen (University of Sheffield)WP5 | User Interface Co-designLead: Dr Talya Porat (Imperial College London)WP6 | Data Integration and ApplicationLeads: Prof. Céire Costelloe (Institute of Cancer Research), Mr Darlington Akogo (minoHealth AISP1 | Evaluation of the detection of asymptomatic carriage of malaria parasites in cross-sectional community screening surveys using a point of care digital diagnostic PhD Student: Dimbintsoa Robinson, MRC Unit The Gambia (LSYTM) – Supervisors: Prof. D'Alessandro, Prof Tinto SP2 | Evaluation of the detection of malaria parasite species and anti-malarial resistance in uncomplicated malaria patients using a point of care digital diagnostic PhD Student: Martin Chamai, University of Ghana, WACCBIP – Supervisors: Dr Amoah, Prof. AwandareSP3 | Evaluation of the detection of malaria in pregnancy and anti-malarial drug resistance using a point of care digital diagnostic PhD Student: Jean-Bertin Kabuya, Tropical Diseases Research Centre – Supervisor: Prof. Christine ManyandoSP4 | Evaluation of detection of P. falciparum and P. Vivax malaria and G6PD deficiency using a point of care digital diagnostic PhD Student: Waleed Mohammed Alhaj Jebreel, University of Khartoum, IEND – Supervisors: Prof. Osman, Prof. MahdiSP5 | Evaluating a digital diagnostic to distinguish between causes of childhood febrile illness PhD Student: Flavian Akite, University of Ghana, WACCBIP – Supervisors: Dr Duodu, Dr Usuf, Dr CunningtonSP6 | Developing and evaluating a digital diagnostic for environmental pathogen detection PhD Student: Erick Odoyo, Masinde Muliro University of Science and Technology (MMUST) – Supervisors: Dr Sifuna, Dr Rodriguez ManzanoSP7 | Evaluating digital diagnostic implementation through national and international health policy & health systems analysis PhD Student: Shola Kelly Molemodile Dele-Olowu, University of Ghana – Supervisors: Dr Balen, Prof. Yeung, Prof. YawsonSP8 | Evaluating digital diagnostic implementation through local health systems and service analysis PhD Student: Mamadu Baldeh, MRC Unit The Gambia (LSYTM) – Supervisors: Dr Balen, Prof de Witte, Prof YeungSP9 | Co-design and development of user interfaces for digital diagnostics PhD Student: Angelina Ankah Amengu, University of Ghana – Supervisors: Dr Porat, Dr AbdulaiSP10 | Integration and application of data from digital diagnostics for disease surveillance and control PhD Student: Francis Dzabeng, University of Ghana – Supervisors: Dr Abdulai, Mr Akogo, Dr Okell, Dr CostelloeThe involvement of community members, as potential end-users of the diagnostics, is central to the codesign process. Wider community engagement will be undertaken for the diagnostic accuracy studiesto ensure that the research is appropriate and approved by the local communities. Imperial College of Science, Technology and Medicine Malaria Consortium National Institute of Health Research (NIHR) MRC Unit The Gambia Masinde Muliro University of Technology and Sciences Mino Health AI University of Nairobi Institut de la Recherche en la Santé, Clinical Unit of Nanoro (IRSS-CRUN) National Health Research and Training Institute (Zambia) The Hague University of Applied Sciences Institute of Cancer Research University of Khartoum Patient Helping Fund Organization Canterbury Christ Church University University of Ghana 2153794 115811 19296 85113 238217 2006806.1 126294 122101 55775.32 110523 403689 142871 53496.86 1473187.18 GB-COH-04465125-NIHRPA7196 Imperial College of Science, Technology and Medicine "Racial/ethnic health inequalities are large, unjust, preventable, and remediable. Health systems can exacerbate these inequalities by reflecting discrimination in wider society or by actively addressing these inequalities. Specific actions are needed to strengthen policies, financing, and clinical services to reduce racial health inequalities. This project will produce evidence on different health system factors and policies that exacerbate or reduce racial health inequalities in Brazil. It specifically aims to: 1) comprehensively measure racial health inequalities across Brazil, including changes over time and between geographical areas; 2) understand and quantify health system factors (e.g. policies, financing, health professionals, and discrimination) which drive these inequalities; 3) evaluate the impact of key national policies on racial health inequalities; 4) produce indicators for measuring racial health inequalities and a visual online dashboard; 5) involve and engage communities, politicians, civil society, and administrators in the research process; and 6) raise awareness and build capacity with online training courses, social media, and seminars. This work will be carried out in Brazil by the Institute of Health Policy Studies (IEPS) in Sao Paulo in collaboration with Imperial College London in the UK. Brazil is a key setting for this research as it has large health inequalities across racial groups and there are high-quality healthcare datasets. There are also important policies related to the health of the Black population that need evaluating, and there are effective civil society movements and engaged policymakers requesting evidence to inform their agendas. Policymakers and politicians, Black movement groups, and civil society informed this project and will join the research team to shape the research priorities, increase their knowledge of research, foster uptake of results, and inform new policies. Outputs include academic papers, technical and policy briefs, online data visualisations, newspaper articles, social media content, targeted discussions with policymakers, and workshops. This strategy aims to equip the Brazilian health system to better tackle racial health inequalities, build capacity of administrators, and empower communities to lead and campaign for change." UK-Department of Health and Social Care Instituto de Estudos Para políticas de Saúde Imperial College London Imperial College London Thomas Hone (PI) t.hone@imperial.ac.uk Instituto de Estudos para Políticas de Saúde (IEPS) Bianca Reis bianca.reis@ieps.org.br Instituto de Estudos para Políticas de Saúde (IEPS) Lucas Falcão Lucas.falcao@ieps.org.br 971456.62 318329.00 412385.06